Is It Safe To Stop Clopidogrel After One Year?

Is it safe to take clopidogrel long term?

Safety Announcement [ 11-06-2015 ] A U.S.

Food and Drug Administration (FDA) review has determined that long-term use of the blood-thinning drug Plavix (clopidogrel) does not increase or decrease overall risk of death in patients with, or at risk for, heart disease..

Is clopidogrel better than aspirin?

In summary, clopidogrel appears to be somewhat more effective than aspirin if one is willing to accept the unitary atherosclerosis paradigm. The gain, however, is modest: about 200 patients should use clopidogrel rather than aspirin for 1 year to prevent just one vascular event.

Why is clopidogrel only prescribed for a year?

Brand name: Plavix. Clopidogrel is used to prevent heart attack and stroke. It’s prescribed for people who have had a recent heart attack or stroke, or who have peripheral arterial disease (poor circulation in the legs).

What will happen if I stop taking clopidogrel?

If you stop taking clopidogrel, the rate at which your blood clots will return to what it was before you started taking it – usually within 5 days of stopping. This means you may be at increased risk of serious problems like heart attacks or strokes.

What is the best time of day to take clopidogrel?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel. Acute-phase reactants were elevated.

Do and don’ts after stent?

Don’t lift heavy objects. Avoid strenuous exercise. Avoid sexual activity for a week. Wait at least a week before swimming or bathing.

Does having stents shorten your life?

Summary: While the placement of stents in newly reopened coronary arteries has been shown to reduce the need for repeat angioplasty procedures, researchers from the Duke Clinical Research Institute have found that stents have no impact on mortality over the long term.

Can you ever stop taking blood thinners?

“With this rule we can confidently tell half of the women we see that they are at low risk of having another blood clot. This means they can stop taking blood thinners once their initial clot is treated, sparing them the cost, inconvenience and risks of taking life-long medication.”

Is it OK to take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.

Does clopidogrel affect blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP).

What are the side effects of clopidogrel 75 mg?

Common side effects of clopidogrel can include:headaches or dizziness.nausea.diarrhoea or constipation.indigestion (dyspepsia)stomach ache or abdominal pain.nosebleeds.increased bleeding (your blood taking longer to clot – for example, when you cut yourself), or easy bruising.

Does clopidogrel make you tired?

Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness. headache.

Is a stent major surgery?

A cardiac stent is used to treat narrowed or blocked coronary arteries. It can also be used to improve blood flow immediately following a heart attack. Cardiac stents are expandable coils made of metal mesh. Your doctor can insert one during a coronary angioplasty, a nonsurgical and minimally invasive procedure.

Does clopidogrel affect the liver?

The severity of liver injury associated with clopidogrel ranges from transient, mild serum enzyme elevations to clinically apparent acute hepatitis that can be severe and lead to death. Most cases resolve with drug withdrawal within 1 to 3 months.

How long should you take clopidogrel after stent placement?

People who have drug-eluting stents need to take medications, such as clopidogrel or ticagrelor, to reduce the risk of stent clotting for at least one year after the stent is inserted. For most people with bare-metal stents, additional anti-clotting medication is only recommended for one month after stent placement.

How long should you take clopidogrel for?

Current guidelines say to take Plavix and aspirin every day for a month after getting a bare-metal stent and daily for at least a year after getting a drug-coated stent to prevent blood clots from forming inside a stent. Called late stent thrombosis, such clots can cause a heart attack or cardiac arrest.

Is there an alternative to clopidogrel?

1). Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.

Which is safer aspirin or clopidogrel?

Interpretation Long-term administration of clopidogrel to patients with atherosclerotic vascular disease is more effective than aspirin in reducing the combined risk of ischaemic stroke, myocardial infarction, or vascular death.

What foods should you avoid if you are on blood thinners?

If you take medicine for your heart, doctors recommend staying away from some foods because of the risk of interaction….Blood thinners: Eat fewer foods with vitamin KAsparagus.Broccoli.Brussels sprouts.Cauliflower.Green onions.Kale.Parsley.Spinach.

Can I stop taking Plavix after 6 months?

How long do I have to take Plavix? Most experts recommend taking Plavix and aspirin for at least one year after getting a stent, unless the drug causes problems. If necessary, it can be stopped after three months with a bare-metal stent or six months with a drug-releasing stent.