Quick Answer: How Do You Know If Clopidogrel Is Working?

Does clopidogrel lower blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP)..

Can I drink coffee with clopidogrel?

Conclusions. Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.

Does clopidogrel affect blood sugar?

The mechanism of glucose lowering activity of clopidogrel is not clear but it could be explained on the basis of clopidogrel inhibitory effect on TNF-α production and this might cause improvement in insulin sensitivity, increase in glucose utilization by peripheral tissue and suppressed hepatic glucose production.

What is the best time of the day to take clopidogrel?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel. Acute-phase reactants were elevated.

What is the difference between aspirin and clopidogrel?

Aspirin and Plavix (clopidogrel bisulfate) are drugs used to prevent blood clots. Aspirin and Plavix belong to different drug classes. Plavix is an anticoagulant and aspirin is a nonsteroidal anti-inflammatory drug (NSAID). Aspirin also is used to reduce fever, and to treat pain and inflammation in the body.

Can you ever stop taking blood thinners?

“With this rule we can confidently tell half of the women we see that they are at low risk of having another blood clot. This means they can stop taking blood thinners once their initial clot is treated, sparing them the cost, inconvenience and risks of taking life-long medication.”

Is clopidogrel a statin?

Statins are lipid-lowering agents, whereas clopidogrel is an antiplatelet agent. Clinicians commonly prescribe both medications for patients to prevent atherosclerotic cardiovascular disease (ASCVD).

How long does it take for clopidogrel to work?

If you take it every day, clopidogrel stops platelets clumping together to form unwanted blood clots. This prevents heart attacks and strokes. How long does it take to work? Clopidogrel works within 2 hours of taking it.

What are the side effects of taking clopidogrel?

Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:excessive tiredness.headache.dizziness.nausea.vomiting.stomach pain.diarrhea.nosebleed.

What can you not take with clopidogrel?

Clopidogrel may interact with other medicationsDiabetes drug. In most cases, repaglinide should not be taken with clopidogrel. … Stomach acid drugs (proton pump inhibitors) … Nonsteroidal anti-inflammatory drugs (NSAIDs) … Blood thinners.Drugs used to treat depression. … Salicylates (aspirin) … Opioids.

Is there an alternative to clopidogrel?

1). Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.

Can you take clopidogrel long term?

Safety Announcement. [ 11-06-2015 ] A U.S. Food and Drug Administration (FDA) review has determined that long-term use of the blood-thinning drug Plavix (clopidogrel) does not increase or decrease overall risk of death in patients with, or at risk for, heart disease.

Does clopidogrel affect the liver?

The severity of liver injury associated with clopidogrel ranges from transient, mild serum enzyme elevations to clinically apparent acute hepatitis that can be severe and lead to death. Most cases resolve with drug withdrawal within 1 to 3 months.

Is it OK to take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.

Is clopidogrel stronger than aspirin?

In summary, clopidogrel appears to be somewhat more effective than aspirin if one is willing to accept the unitary atherosclerosis paradigm. The gain, however, is modest: about 200 patients should use clopidogrel rather than aspirin for 1 year to prevent just one vascular event.

What foods should you avoid if you are on blood thinners?

If you take medicine for your heart, doctors recommend staying away from some foods because of the risk of interaction….Blood thinners: Eat fewer foods with vitamin KAsparagus.Broccoli.Brussels sprouts.Cauliflower.Green onions.Kale.Parsley.Spinach.

How long should one take clopidogrel?

The new recommendation is that after 12 months if there is no evidence of major bleeding or other problems with clopidogrel + aspirin, it is suggested you continue that therapy for an additional 18 months. I know, it seems long.